6-Bromo-2,3-dihydro-1,3-benzothiazol-2-one → 6-(3-Chloro-phenyl)-3H-benzothiazol-2-one

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Reaction Steps

Prepared from 6-bromo-2-benzothiazolinone, 3-chlorophenyl boronic acid according to the procedure of example 12. A white solid: mp 195-196° C.; 1H-NMR (DMSO-d6) δ11.95 (s, 1H), 7.96 (d, 1H, J=1.17 Hz), 7.7 (t, 1H, J=1.76 Hz), 7.62-7.59 (m, 2H), 7.46 (t, 1H, J=7.65 Hz), 7.4-7.38 (m, 1H), 7.18 (d, 1H, J=8.24 Hz); MS (EI) m/z (M+, 30%); Anal. Calc. For C13H8ClNOS.H2O: C, 57.67; H, 3.35; N, 5.17. Found: C, 57.98; H, 3.11; N, 4.98.

Provenance & Evidence