Methyl Isocyanate → HCID 44242163, compound

HRID 84419Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH:12]=[N:11][N:10]=[C:9]1[C:13]1[S:27][C:16]2[C:17]3[CH:25]=[CH:24][C:23]([NH2:26])=[CH:22][C:18]=3[O:19][CH2:20][CH2:21][C:15]=2[CH:14]=1.[CH3:28][N:29]=[C:30]=[O:31]>>[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[N:8]1[CH:12]=[N:11][N:10]=[C:9]1[C:13]1[S:27][C:16]2[C:17]3[CH:25]=[CH:24][C:23]([NH:26][C:30]([NH:29][CH3:28])=[O:31])=[CH:22][C:18]=3[O:19][CH2:20][CH2:21][C:15]=2[CH:14]=1

Participants

Reactant 2

HCID 12228Methyl Isocyanate

HCID 57900115HCID 57900115, compound

Product 1

HCID 44242163HCID 44242163, compound

Procedure

Following the procedures of Example 76, 2-(4-(2-chlorophenyl)-4H-1,2,4-triazol-3-yl)-4,5-dihydrobenzo[b]thieno[2,3-d]oxepin-8-amine was reacted with methyl isocyanate to give 112. MS: (ESI+) 452.1

Sources & evidence

ORD record: ord-94f7f924c8b9462c9615b27316330d8d
Source dataset: uspto-grants-2014_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08846762B2

Reaction notes

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