6-Ethylthio-5-fluoroindole-2,3-dione → 6-Ethylthio-5-fluoroindole

Participants

Reaction Steps

6-Ethylthio-5-fluoroindole was prepared from 6-ethylthio-5-fluoroindole-2,3-dione according to the method described in the synthesis of 7-chloro-5-fluoroindole as a pale green oil (0.49 g, 23%): IR νmax (film)/cm−1 3426, 2969, 2927, 1565, 1471, 1454, 1307, 1140 and 1101; NMR δH (400 MHz, CDCl3) 1.26 (3H, t, J 7.5), 2.91 (2H, q, J 7.5 Hz), 6.48-6.51 (1H, m), 7.23 (1H, t, J 2.5 Hz), 7.31 (1H, d, J 10.0 Hz), 7.46 (1H, d, J 6.0 Hz), 8.01-8.25 (1H, brm).

Provenance & Evidence