HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrothiopyran-4-one → HCID 9796492, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrothiopyran-4-one | HCID 66173 | — |
| Reactant | 4-(1H-Indol-6-yl)thian-4-ol | HCID 40425148 | — |
| Reactant | HCID 54251766 | HCID 54251766 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | HCID 9796492 | HCID 9796492 | — |
Reaction Steps
1-(N-Cyclopropylamino)ethyl)-6-(4-hydroxy-tetrahydrothiopyran-4-yl)-1H-indole: (34.2 mg, 8%); from 6-bromo-1-(N-Cyclopropylamino)ethyl indole (400.0 mg, 1.32 mmol), nBuLi (2.5M, 1.32 mL, 3.30 mmol) and tetrahydrothiopyran-4-one (760.0 mg, 6.59 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06380242B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-0549684dd1de42bdad5f4113778c760a |
| Source note | uspto-grants-2002_04 |