3-(1,3,2-Dioxaborinan-2-yl)pyridine → HCID 18007544, compound

HRID 844244Notes

Reaction equation

HRID 844244 reaction equation
Br[C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[CH:7][N:8]2[CH2:11][CH2:12][CH2:13][N:14]([CH3:16])[CH3:15])=[CH:4][CH:3]=1.B1([C:23]2[CH:28]=[CH:27][CH:26]=[N:25][CH:24]=2)OCCCO1>>[CH3:15][N:14]([CH2:13][CH2:12][CH2:11][N:8]1[C:9]2[C:5](=[CH:4][CH:3]=[C:2]([C:23]3[CH:24]=[N:25][CH:26]=[CH:27][CH:28]=3)[CH:10]=2)[CH:6]=[CH:7]1)[CH3:16]

Participants

3

Reactant 2

HCID 41980053-(1,3,2-Dioxaborinan-2-yl)pyridineHCID 18007591HCID 18007591, compound

Product 1

HCID 18007544HCID 18007544, compound

Procedure

(9.8 mg, 13%); from 6-bromo-1-(3-(N,N-dimethylamino)propyl) indole (75.0 mg, 0.267 mmol) and pyridine-3-boronic acid 1,3-propanediol cyclic ester (87.0 mg, 0.534 mmol).

Sources & evidence

ORD record
ord-706401ce826046c299da708e263bbc2b
Source dataset
uspto-grants-2002_04
Patent number
US06380242B1

Reaction notes

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