3-(1,3,2-Dioxaborinan-2-yl)pyridine → HCID 18007513, compound

HRID 844245Notes

Reaction equation

HRID 844245 reaction equation
Br[C:2]1[CH:10]=[C:9]2[C:5]([CH:6]=[C:7](C(C3CCCN3)C)[NH:8]2)=[CH:4][CH:3]=1.B1([C:24]2[CH:29]=[CH:28][CH:27]=[N:26][CH:25]=2)OCCCO1>>[NH:8]1[CH2:7][CH2:6][CH2:5][CH:9]1[CH:10]([N:8]1[C:9]2[C:5](=[CH:4][CH:3]=[C:2]([C:28]3[CH:27]=[N:26][CH:25]=[CH:24][CH:29]=3)[CH:10]=2)[CH:6]=[CH:7]1)[CH3:2]

Participants

3

Reactant 2

HCID 41980053-(1,3,2-Dioxaborinan-2-yl)pyridineHCID 70035657HCID 70035657, compound

Product 1

HCID 18007513HCID 18007513, compound

Procedure

(9.3 mg, 49%); from 6-Bromo-1-(2-pyrrolidinyl)ethyl indole (19.0 mg, 0.065 mmol) and pyridine-3-boronic acid 1,3-propanediol cyclic ester (21.0 mg, 0.130 mmol).

Sources & evidence

ORD record
ord-ae43a178baef4dc89f78b8a2f697a5c7
Source dataset
uspto-grants-2002_04
Patent number
US06380242B1

Reaction notes

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