Water → HCID 54380114, compound

HRID 844300Notes

Reaction equation

HRID 844300 reaction equation
[CH3:1][S:2][C:3]1[CH:24]=[CH:23][CH:22]=[CH:21][C:4]=1[C:5]([NH:7][C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:15](=[O:20])C(F)(F)F)=[CH:10][CH:9]=1)=[O:6].I([O-])(=O)(=O)=O.[Na+].[OH2:31]>>[C:4]([O:20][C:15](=[O:31])[NH:14][C:11]1[CH:12]=[CH:13][C:8]([NH:7][C:5](=[O:6])[C:4]2[CH:21]=[CH:22][CH:23]=[CH:24][C:3]=2[S:2][CH3:1])=[CH:9][CH:10]=1)([CH3:21])([CH3:5])[CH3:3]

Participants

4

Reactant 3

HCID 962WaterHCID 18542858HCID 18542858, compoundHCID 23667635Sodium periodate

Product 1

HCID 54380114HCID 54380114, compound

Procedure

To a solution of 2-methylsulfanyl-N-[4-(2,2,2-trifluoro-acetylamino)-phenyl]-benzamide (234 mg) is added a saturated solution of sodium periodate (5 mL) and the mixture is stirred for 12 hours. The purple mixture is poured into water, extracted with ethyl acetate, dried over anhydrous potassium carbonate and evaporated to yield a red solid, 101 mg.

Workup

  1. extractionextracted with ethyl acetate
  2. dry with materialdried over anhydrous potassium carbonate
  3. customevaporated
  4. customto yield a red solid, 101 mg

Sources & evidence

ORD record
ord-802d32a9fb3042588aa7e5628b2b88f8
Source dataset
uspto-grants-2002_04
Patent number
US06380243B1

Reaction notes

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