HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22322686, compound → HCID 69854456, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22322686 | HCID 22322686 | — |
| Reactant | HCID 69854658 | HCID 69854658 | — |
| Solvent | Water | HCID 962 | — |
| Product | HCID 69854456 | HCID 69854456 | 92% |
Reaction Steps
According to the procedures described for 4a the reaction of ester 3b (40 mg, 0.99 mmol) and lithium hydroxide hydroxide (0.40 mL of a 0.5 N solution in H2O, 0.20 mmol) afforded 35.6 mg (92%) of the title compound after purification by flash column chromatography (silica gel, 100% EtOAc).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06380250B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-05caaa1ddef246b1a6ae90a7240c942c |
| Source note | uspto-grants-2002_04 |