Ethylamine → HCID 10276847, compound

HRID 844351Notes

Reaction equation

[Cl:1][C:2]1[CH:3]=[C:4]([CH:39]=[CH:40][CH:41]=1)[CH2:5][NH:6][C:7]([O:9][CH2:10][C@@H:11]1[C@@H:15]([O:16]C2CCCCO2)[CH2:14][C@@H:13]([O:23]C2CCCCO2)[C@H:12]1[CH2:30]/[CH:31]=[CH:32]\[CH2:33][CH2:34][CH2:35][C:36]([OH:38])=O)=[S:8].[CH2:42]([NH2:44])[CH3:43]>>[CH2:42]([NH:44][C:36]([CH2:35][CH2:34][CH2:33]/[CH:32]=[CH:31]\[CH2:30][C@H:12]1[C@@H:13]([OH:23])[CH2:14][C@@H:15]([OH:16])[C@@H:11]1[CH2:10][O:9][C:7](=[S:8])[NH:6][CH2:5][C:4]1[CH:39]=[CH:40][CH:41]=[C:2]([Cl:1])[CH:3]=1)=[O:38])[CH3:43]

Participants

Reactant 2

HCID 6341Ethylamine

HCID 86585191HCID 86585191, compound

Product 1

HCID 10276847HCID 10276847, compound

Procedure

According to the procedures described above in Examples 17 and 18 acid 7 was converted with use of ethylamine to 30 mg of the above titled compound.

Sources & evidence

ORD record: ord-180d7b9e53914aaaa70528a794dbc993
Source dataset: uspto-grants-2002_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06380251B1

Reaction notes

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