Sodium Hydroxide → HCID 9861952, compound

HRID 844359Notes

Reaction equation

HRID 844359 reaction equation
C([O:3][C:4](=[O:26])[C:5](=[O:25])[CH2:6][C:7](=[O:24])[C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH:14]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH2:17][CH2:16][CH2:15]2)[CH:9]=1)C.[OH-].[Na+]>CO>[O:25]=[C:5]([CH2:6][C:7](=[O:24])[C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([CH:14]2[C:23]3[C:18](=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH2:17][CH2:16][CH2:15]2)[CH:9]=1)[C:4]([OH:26])=[O:3]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 18736271HCID 18736271, compound

Product 1

HCID 9861952HCID 9861952, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Isomer B: In a similar manner to the above, 2,4-dioxo-4-[3-(1,2,3,4-tetrahydronaphthalen-1-yl)-phenyl]butyric acid ethyl ester (isomer B from above) was reacted in 2 mL methanol with 1 mL 1M sodium hydroxide to afford the title compound as a yellow solid.

Sources & evidence

ORD record
ord-8da485fe3933454a84bde926f61af8de
Source dataset
uspto-grants-2002_04
Patent number
US06380249B1

Reaction notes

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