HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 844383Generated: October 25, 2026
Gamma-Butyrolactone → N-butyl-4-hydroxybutanamide
https://huagongshe.com/reaction/844383
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Gamma-Butyrolactone | HCID 7302 | — |
| Reactant | Butylamine | HCID 8007 | — |
| Product | N-butyl-4-hydroxybutanamide | HCID 13060238 | — |
Reaction Steps
To 30 mL (390 mmol) of g-butyrolactone was added 45 ml (455 mmol) of n-butylamine. The solution was heated at 85° C. for 1.5 hr, then the excess n-butylamine was removed in vacuo. The product crystallized on standing to give about 62 g of a colorless, low melting solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US06380241B1 |
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| Source dataset | uspto-grants-2002_04 |
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| ORD ID | ord-e65ff8bacf6f4e67986c6501b4e19eef |
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| Source note | uspto-grants-2002_04 |
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