HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 844394Generated: October 27, 2026
p-Toluenesulfonic acid → 3-hydroxy-N'-(1-methylethylidene)-2-naphthohydrazide
https://huagongshe.com/reaction/844394
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | p-Toluenesulfonic acid | HCID 6101 | — |
| Reactant | 3-Hydroxy-2-naphthoic acid hydrazide | HCID 72699 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 3-hydroxy-N'-(1-methylethylidene)-2-naphthohydrazide | HCID 4521975 | — |
Reaction Steps
A four neck flask (3 liters) equipped with a thermometer, a reflux condenser and a stirrer was charged with 121.2 g (0.6 mol) of 3-hydroxy-2-naphthohydrazide, 1.14 g (0.006 mol) of p-toluenesulfonic acid and 2 liters of acetone and then heated under reflux for 5 hours. The reaction liquid was cooled down to 20° C. or lower, and then crystal was filtered off and dried under reduced pressure, whereby the intended compound (slightly yellow crystal) was obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US06380288B1 |
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| Source dataset | uspto-grants-2002_04 |
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| ORD ID | ord-5d6f44b48cc54f7980cfe0dbf05aba55 |
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| Source note | uspto-grants-2002_04 |
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