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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 844439Generated: October 29, 2026

1,2,4-Trimethyl-5-nitrobenzene → 2,4,5-Trimethylaniline

https://huagongshe.com/reaction/844439

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,4-Trimethyl-5-nitrobenzeneHCID 69130—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product2,4,5-TrimethylanilineHCID 871797.2%

Reaction Steps

19.70 g of 2,4,5-trimethylnitrobenzene are dissolved in 500 ml of ethanol and the solution is then hydrogenated at room temperature and pressure in the presence of 1 g of 5% Pd/C. The catalyst is filtered off on Celite® and the medium is then evaporated to give 15.67 g of the expected compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06380230B1
Source datasetuspto-grants-2002_04
ORD IDord-2587545f4ab348df9337b2853650d7ab
Source noteuspto-grants-2002_04