HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → 8-Cyclopropyl-6-ethynyl-2,2,4,4-tetramethylchroman
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 8-Cyclopropyl-6-trimethylsilanylethynyl-2,2,4,4-tetramethyl chroman | HCID 18719789 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 8-Cyclopropyl-6-ethynyl-2,2,4,4-tetramethylchroman | HCID 22569006 | — |
Reaction Steps
Following general procedure E and using 8-cyclopropyl-6-trimethylsilanylethynyl-2,2,4,4-tetramethyl chroman (Intermediate 33, 0.17 g, 0.68 mmol), methanol and potassium carbonate (0.2 g, 1.47 mmol) the title compound was obtained as an oil (0.064 g, 47%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06380256B1 |
| Source dataset | uspto-grants-2002_04 |
| ORD ID | ord-4194b69ce306416f8c563569780f7a64 |
| Source note | uspto-grants-2002_04 |