2-Bromo-5-methoxybenzoic acid → HCID 69336716, compound

HRID 844843Notes

Reaction equation

HRID 844843 reaction equation
C[O:2][C:3](=[O:23])[C@H:4]([CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:14](=[O:22])[N:15]([CH3:21])[C:16](=[O:20])[N:17]([CH3:19])[CH:18]=2)=[CH:9][CH:8]=1)[NH2:5].[Br:24][C:25]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[CH:30][C:26]=1[C:27](O)=[O:28]>>[Br:24][C:25]1[CH:33]=[CH:32][C:31]([O:34][CH3:35])=[CH:30][C:26]=1[C:27]([NH:5][C@H:4]([C:3]([OH:2])=[O:23])[CH2:6][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[C:14](=[O:22])[N:15]([CH3:21])[C:16](=[O:20])[N:17]([CH3:19])[CH:18]=2)=[CH:9][CH:8]=1)=[O:28]

Participants

3

Reactant 2

HCID 899062-Bromo-5-methoxybenzoic acidHCID 69336859HCID 69336859, compound

Product 1

HCID 69336716HCID 69336716, compound

Procedure

N-[(2-bromo-5-methoxyphenyl)carbonyl]-4-[1,3-dimethyl-2,4-dioxo-5-pyrimidinyl]-L-phenylalanine was prepared from 4-[1,3-dimethyl-2,4-dioxo-5-pyrimidinyl]-L-phenylalanine methyl ester and 2-bromo-5-methoxybenzoic acid using the general procedures described in example 2. EI-HRMS m/e calcd for C23H22N3O6Br (M+H) 516.0770, found 516.0780.

Sources & evidence

ORD record
ord-0184e6c1789e443c973032b5923066b4
Source dataset
uspto-grants-2002_04
Patent number
US06380387B1

Reaction notes

Loading…