Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrogen Peroxide → 4-Piperidinol, 1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethyl-
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrogen Peroxide | HCID 784 | — |
| 반응물 | 1,4-Dihydroxy-2,2,6,6-tetramethylpiperidine | HCID 5395 | — |
| 반응물 | tert-Butanol | HCID 6386 | — |
| 반응물 | Sodium Sulfite | HCID 24437 | — |
| 생성물 | 4-Piperidinol, 1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethyl- | HCID 6850828 | — |
반응 단계
A solution of 50% aqueous hydrogen peroxide is added to a mixture of 4-hydroxy-1-oxyl-2,2,6,6-tetramethylpiperidine and ferrous chloride tetrahydrate in tert-butyl alcohol at 30-60° C. Excess peroxide is decomposed with aqueous sodium sulfite. The organic layer is concentrated and the crude product is purified by flash chromatography on silica gel to afford a sample of 4-hydroxy-1-(2-hydroxy-2-methylpropoxy)-2,2,6,6-tetramethylpiperidine.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US06380389B2 |
| 출처 데이터셋 | uspto-grants-2002_04 |
| ORD ID | ord-12e5559395e44cb786276d34c64cef85 |
| 출처 메모 | uspto-grants-2002_04 |