Phosphorus oxychloride → 2-Benzylthio-6,7-dichloro-5-methyl-1,2,4-triazolo[1,5-a]pyrimidine

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Reaction Steps

This material was prepared in 68% yield from 2-benzylthio-6-chloro-7-hydroxy-5-methyl-1,2,4-triazolo[1,5-a]pyrimidine and phosphorus oxychloride following the general procedure described in Example 20. The desired product was isolated as a solid, m.p. 103°-105° C. IR and 1H NMR spectra were in agreement with the assigned structure.

Provenance & Evidence