HCID 10497335, compound → HCID 14155093, compound

HRID 844970Notes

Reaction equation

HRID 844970 reaction equation
[CH2:1]([S:8][C:9]1[N:23]=[C:12]2[N:13]=[C:14]([O:17][CH2:18][C:19](F)(F)F)[CH:15]=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>C(O)C>[CH2:1]([S:8][C:9]1[N:23]=[C:12]2[N:13]=[C:14]([O:17][CH2:18][CH3:19])[CH:15]=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 10497335HCID 10497335, compound

Product 1

HCID 14155093HCID 14155093, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

This material was prepared by heating 2-benzylthio-5-(2,2,2-trifluoroethoxy)-1,2,4-triazolo[1,5-a]pyrimidine in boiling ethanol. The hot mixture was filtered and the filtrate was concentrated. The crude product was recrystallized from isopropanol to yield the desired product as a solid, m.p. 115°-117° C. IR and 1HNMR spectra were in agreement with the assigned structure.

Workup

  1. customThis material was prepared
  2. filtrationThe hot mixture was filtered
  3. concentrationthe filtrate was concentrated
  4. customThe crude product was recrystallized from isopropanol

Sources & evidence

ORD record
ord-077f3e0f7b06463a9d9261f87982cd4d
Source dataset
uspto-grants-1988_07
Patent number
US04755212

Reaction notes

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