HCID 10708664, compound → HCID 10660873, compound

HRID 844972Notes

Reaction equation

[CH2:1]([S:8][C:9]1[N:19]=[C:12]2[N:13]=[C:14](Cl)[C:15]([CH3:17])=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH3:20][O-:21].[Na+]>>[CH2:1]([S:8][C:9]1[N:19]=[C:12]2[N:13]=[C:14]([O:21][CH3:20])[C:15]([CH3:17])=[CH:16][N:11]2[N:10]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

Reactant 2

HCID 10708664HCID 10708664, compound

HCID 10942334Sodium Methoxide

Product 1

HCID 10660873HCID 10660873, compoundYield 64%

Procedure

This material was prepared in 64% yield by reaction of 2-benzylthio-5-chloro-6-methyl-1,2,4-triazolo[1,5-a]pyrimidine with sodium methoxide following the general procedure described in Example 22. The desired product was isolated as a solid, m.p. 145°-146° C. IR and 1H NMR spectra were in agreement with the assigned structure.

Sources & evidence

ORD record: ord-2badecba2c6645f68a727a8d6027fd7d
Source dataset: uspto-grants-1988_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04755212

Reaction notes

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