Potassium Carbonate → HCID 19837376, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 29.4 g (0.200 mol) of 2-fluoro nitrobenzene, 41.0 g (0.200 mol) of 2-chloro-4-trifluoromethylphenol and 30.0 g (0.220 mol) of K2CO3 in 150 ml of DMSO was heated at 100° C. for 6 hours. The reaction mixture was poured over ice and extracted with ether. The organic phase was washed with water and saturated aqueous NaCl and dried (MgSO4). The solvent was removed by evaporation at reduced pressure to yield 56.1 g (88%) of the desired product as a yellow oil. IR and 1H NMR spectra were in agreement with the assigned structure.

Provenance & Evidence