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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 845001Generated: November 1, 2026

1,3-Difluoro-2-nitrobenzene → 2-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzene

https://huagongshe.com/reaction/845001

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-Difluoro-2-nitrobenzeneHCID 87922—
Reactant2-Chloro-4-(trifluoromethyl)phenolHCID 2736603—
Product2-(2-Chloro-4-trifluoromethylphenoxy)-6-fluoronitrobenzeneHCID 54137414—

Reaction Steps

This material was prepared in 47% yeild from 2,6-difluoronitrobenzene and 2-chloro-4-trifluoromethylphenol following the general procedure outlined in Example 88. The product was isolated as an oil which was characterized by IR and 1H NMR spectroscopy.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04755212
Source datasetuspto-grants-1988_07
ORD IDord-d7bc800ac3a94afb9e8284dbdc12b861
Source noteuspto-grants-1988_07