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HRID845006

反应详情

EQUATION

反应方程式

HRID 845006 的结构方程式

REACTANTS

反应物

3
结构：C(=NC1CCCCC1)=NC1CCCCC1
HCID10868

Dicyclohexylcarbodiimide

C13H22N2

结构：CCCCC[C@@H]1CO[C@@H](c2ccc(C(=O)O)cc2F)CO1
HCID70418790

未命名化合物

结构：CCC[C@H]1CC[C@H](O)CC1
HCID178448131

未命名化合物

PRODUCTS

生成物

1
结构：CCCCC[C@@H]1CO[C@@H](c2ccc(C(=O)O[C@H]3CC[C@H](CCC)CC3)cc2F)CO1
HCID178444583

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOCC
溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

A mixture of 2.96 g. 3-fluoro-4-(trans-5-pentyl-1,4-dioxane-2-yl)benzoic acid (obtainable from the nitrile, cf. Example 7), 1.42 g. trans-4-propylcyclohexanol and 2.06 g. dicyclohexylcarbodiimide is boiled in 50 ml. diethyl ether for 6 hours. After cooling, one filters, works up as usual and obtains 3-fluoro-4-(trans-5-pentyl-1,4-dioxan-2-yl)benzoic acid trans-4-propylcyclohexyl ester.

WORKUP

后处理

  1. additionA mixture of 2.96 g
  2. temperatureAfter cooling