Toluene → HCID 178444584, compound

Participants

Reaction Steps

One boils 27.8 g. (trans-5-pentyl-1,4-dioxanyl)-benzoic acid (obtainable by reaction of trans-2-phenyl-5-pentyl-1,4-dioxane with CH3COCl/AlCl3 to give 2-p-acetylphenyl-5-pentyl-1,4-dioxane and decomposition with bromine/KOH) for 1 hour with 24 g. SOCl2, dissolves the crude acid chloride obtained in 150 ml. toluene, mixes with 8 ml. pyridine and 16.6 g. trans-4-pentylcyclohexanol and boils for 2 hours. After cooling and usual working up, one obtains p-(trans-5-pentyl-1,4-dioxan-2-yl)-benzoic acid trans-4-pentylcyclohexyl ester.

Provenance & Evidence