HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → trans-2-p-Cyanophenyl-5-pentyl-1,4-dioxane
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | Cyanogen | HCID 9999 | — |
| Reactant | trans-2-p-Bromophenyl-5-pentyl-1,4-dioxane | HCID 86742258 | — |
| Solvent | N-methyl-2-pyrrolidone | HCID 13387 | — |
| Product | trans-2-p-Cyanophenyl-5-pentyl-1,4-dioxane | HCID 86742257 | — |
Reaction Steps
A mixture of 31.3 g. trans-2-p-bromophenyl-5-pentyl-1,4-dioxane, 10 g. Cu2 (CN)2, 120 ml. pyridine and 60 ml. N-methylpyrrolidone is heated for 2 hours to 150°. One cools, adds thereto a solution of 120 g. FeCl3.6H2O in 600 ml. 20% hydrochloric acid, heats to 70° for 1.5 hours, while stirring. Works up as usu 1 and obtains trans-2-p-cyanophenyl-5-pentyl-1,4-dioxane.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04755323 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-7710397969054b5c91874984c6919d8f |
| Source note | uspto-grants-1988_07 |