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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 845037Generated: October 30, 2026

Thiophene-3-carboxylic acid → 1H-Purine-2,6-dione, 3,7-dihydro-1,3-dipropyl-8-(3-thienyl)-

https://huagongshe.com/reaction/845037

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiophene-3-carboxylic acidHCID 6918—
Reactant5,6-Diamino-1,3-dipropyl-2,4(1H,3H)-pyrimidinedioneHCID 5098605—
Product1H-Purine-2,6-dione, 3,7-dihydro-1,3-dipropyl-8-(3-thienyl)-HCID 9905082—

Reaction Steps

The starting 1,3-dipropyl-8-(3-thienyl)xanthine is prepared in a manner analogous to that described in Example 2 hereinafter using 3-thiophenecarboxylic acid and 5,6-diamino-1,3-dipropyluracil, mp>250° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04755517
Source datasetuspto-grants-1988_07
ORD IDord-7ce888016d45424b81c8b05195ddb6b5
Source noteuspto-grants-1988_07