HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrazine hydrate (1:1) → HCID 135707805, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 6-Hydroxy-3,4-dihydro-1(2H)-naphthalenone | HCID 4679494 | — |
| Reactant | Glyoxylic acid, monohydrate | HCID 15620607 | — |
| Product | HCID 135707805 | HCID 135707805 | — |
Reaction Steps
In a manner similar to that given in Preparation 3, 6-hydroxy-1-tetralone was treated with glyoxylic acid monohydrate and hydrazine hydrate to give 5,6-dihydro-8-hydroxybenzo[h]cinnolin-3[2H]-one (m.p. 300°, from dimethylformamide/ethanol); ν(Nujol mull) 3400-2000, 1652, 1594, and 1582cm-1 ; δ(DMSO-d6) 2.77 (4H,s,5,6-H2), 6.65 (2H,m, 4,7-H), 6.74 (1H,m,9-H), 7.73 (1H,d,10-H), 9.93 (1H,d(br),OH), 12.7 (1H,d(br)NH).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04755511 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-06980480a7d144d9bd700695d9fe5c0b |
| Source note | uspto-grants-1988_07 |