Methyl 2-(benzylamino)acetate → Methyl[[3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]propyl](phenylmethyl)amino]acetate

HRID 845094Notes

Reaction equation

HRID 845094 reaction equation
[CH3:1][C:2]([C:5]1[CH:6]=[C:7]([S:16][CH2:17][CH2:18][CH:19]=O)[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]=1[OH:11])([CH3:4])[CH3:3].[CH3:21][O:22][C:23](=[O:33])[CH2:24][NH:25][CH2:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1>CO>[CH3:21][O:22][C:23](=[O:33])[CH2:24][N:25]([CH2:19][CH2:18][CH2:17][S:16][C:7]1[CH:8]=[C:9]([C:12]([CH3:15])([CH3:14])[CH3:13])[C:10]([OH:11])=[C:5]([C:2]([CH3:1])([CH3:4])[CH3:3])[CH:6]=1)[CH2:26][C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1

Participants

4

Reactant 2

HCID 422659Methyl 2-(benzylamino)acetateHCID 140118163-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]propanal

Product 1

HCID 20133530Methyl[[3-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]propyl](phenylmethyl)amino]acetate

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Using the method of Example 39, the product from Example 38 was reacted with methanol and N-benzylglycine methyl ester to give the title compound.

Sources & evidence

ORD record
ord-e45e1c73507a48bcaa4bf409694e8065
Source dataset
uspto-grants-1988_07
Patent number
US04755524

Reaction notes

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