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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 845119Generated: October 30, 2026

1,3-Dibromopropane → 1-[1-(3-Chlorophenyl)cyclobutyl]methanamine

https://huagongshe.com/reaction/845119

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,3-DibromopropaneHCID 8001—
Reactantm-ChlorophenylacetonitrileHCID 73722—
Product1-[1-(3-Chlorophenyl)cyclobutyl]methanamineHCID 15611177—

Reaction Steps

(1-(3-Chlorophenyl)cyclobutyl)methylamine is prepared from (3-chlorophenyl)acetonitrile (3.79 g, 25 mmol) and 1,3-dibromopropane (7.57 g, 375 mmol) as described in Example 1 in 60% overall yield.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04755594
Source datasetuspto-grants-1988_07
ORD IDord-5bf2cecc76e64a21977aadad3dbce7ad
Source noteuspto-grants-1988_07