6-Chloropurine riboside → HCID 15611199, compound

Participants

Reaction Steps

The above amine (1.96 g, 10 mmol) is reacted with 6-chloropurine riboside (2.87 g, 10 mmol) and purified as described in Examples 1 and 7 above. N6-((1-(3-chlorophenyl)cyclobutyl)methyl)adenosine (3.66 g, 82%) as a pale yellow solid foam is obtained m.p. 92°-8° C. Found: C, 56.11; H, 5.33; N, 15.44; Cl, 8.99%. C21H24ClN5O4 calculated requires: C, 56.57; H, 5.39; N, 15.71; Cl, 7.97%.

Provenance & Evidence