1-Phenylcyclohexanecarbonitrile → Cyclohexanemethylamine, 1-phenyl-

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Reaction Steps

1-Phenylcyclohexane carbonitrile is reduced with H2 in methanol containing 16% ammonia with a Raney nickel catalyst. The catalyst is filtered off and (1-phenylcyclohexyl)methylamine is precipitated as its hydrochloride salt m.p. 230°-33° C., by treatment with methanolic HCl and isopropyl ether.

Provenance & Evidence