Toluene → HCID 54006026, compound

Participants

Reaction Conditions

Reaction Steps

Into a 3 liter reaction vessel equipped with stirrer, reflux condenser, thermometer and heating mantle are placed 2000 grams of isopropyl alcohol and 75 grams of aluminum triisopropylate. The resulting mixture is heated to reflux and while refluxing, over a period of 1.5 hours, 500 grams of the aldehyde having the structure: ##STR72## is added slowly to the reaction mass. At the end of the feed period of the aldehyde, solvent is commenced to be stripped at the ratio of 3:1 to a pot temperature of 130° C. The stripping takes place over a period of 5.5 hours. At the end of the 5.5 hour period, the reaction mass is cooled to 80° C. and 500 ml toluene and 150 grams of 50% aqueous sodium hydroxide and 150 grams of water is added to the reaction mass. The reaction mass is refluxed for a period of one hour and then cooled to room temperature.

Provenance & Evidence