HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropanol → 1-(3-Methoxypyridin-2-yl)piperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropanol | HCID 3776 | — |
| Reactant | Piperazine | HCID 4837 | — |
| Reactant | 2-Chloro-3-phenylpyridine | HCID 2762807 | — |
| Product | 1-(3-Methoxypyridin-2-yl)piperazine | HCID 12790495 | — |
Reaction Steps
The 2-chloro-3-methoxypyridine (VI) was treated with piperazine in a refluxing isopropanol medium according to the procedure of Example 3 and, following a similar work-up, gave the desired IIIc intermmediate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04757073 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-1e2287df4af74832ae6c5bd4c80d62de |
| Source note | uspto-grants-1988_07 |