2-Methylpropyl 2-[(3-nitrophenyl)methylidene]-3-oxobutanoate → HCID 20132455, compound

HRID 845271Notes

Reaction equation

HRID 845271 reaction equation
[CH2:1]([O:5][C:6](=[O:21])[C:7](=[CH:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=1)[C:8]([CH3:10])=O)[CH:2]([CH3:4])[CH3:3].[C:22]1(=[O:45])[N:26]([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][O:33][C:34](=[O:39])/[CH:35]=[C:36](\[NH2:38])/[CH3:37])[C:25](=[O:40])[C:24]2=[CH:41][CH:42]=[CH:43][CH:44]=[C:23]12>>[CH3:10][C:8]1[NH:38][C:36]([CH3:37])=[C:35]([C:34]([O:33][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][N:26]2[C:22](=[O:45])[C:23]3=[CH:44][CH:43]=[CH:42][CH:41]=[C:24]3[C:25]2=[O:40])=[O:39])[CH:11]([C:12]2[CH:17]=[CH:16][CH:15]=[C:14]([N+:18]([O-:20])=[O:19])[CH:13]=2)[C:7]=1[C:6]([O:5][CH2:1][CH:2]([CH3:4])[CH3:3])=[O:21]

Participants

3

Reactant 2

HCID 538170092-Methylpropyl 2-[(3-nitrophenyl)methylidene]-3-oxobutanoateHCID 67903369HCID 67903369, compound

Product 1

HCID 20132455HCID 20132455, compound

Procedure

Prepared by a method analogous to that of Example 1(a) from 7.0 g (24 mmol) of 2-(3-nitrobenzylidene)-acetoacetic acid isobutylester and 8.0 g (24 mmol) of 3-amino-crotonic acid-(6-phthalimidohexyl)ester. 14.6 g (quantitative) of an orange yellow oil which is used for further reactions without purification.

Workup

  1. custom14.6 g (quantitative) of an orange yellow oil which is used for further reactions without purification

Sources & evidence

ORD record
ord-ba51a7f9d6574c83918fca5e1da84283
Source dataset
uspto-grants-1988_07
Patent number
US04757080

Reaction notes

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