tert-Butyl isocyanate → HCID 14560820, compound

Participants

Reaction Steps

The product of Example 12 (0.25 g, 0.78 mmol) was dissolved in 1.5 ml of dichloromethane and treated with 90 μl (0.78 mmol) of tert-butylisocyanate, and then heated under reflux overnight. The crystalline product, (±)-α-[[[(1,1-dimethylethyl)amino]carbonyl]-amino ]-α-methyl-N-(2-phenylethyl)-1H-indole-3-propanamide, separated and was collected by filtration and dried.

Provenance & Evidence