反应详情

A mixture of 500 g of methyl anthranilate and 438 g of 2,5-dimethoxytetrahydrofuran in 670 ml of glacial acetic acid is heated at reflux temperature for 11/2 hours. The acetic acid is then evaporated under reduced pressure and the residue is distilled to yield methyl 2-(1H-pyrrol-1-yl)-benzoate, b.p. 109°/0.1 mm Hg.

1. temperatureis heated
2. temperatureat reflux temperature for 11/2 hours
3. customThe acetic acid is then evaporated under reduced pressure
4. distillationthe residue is distilled