Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethanol → 2-Acetylpyridine 4-(2-morpholinoethyl)thiosemicarbazone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethanol | HCID 702 | — |
| 반응물 | 2-Acetylpyridine | HCID 14286 | — |
| 반응물 | 3-Amino-1-(2-(morpholin-4-yl)ethyl)thiourea | HCID 736209 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-Acetylpyridine 4-(2-morpholinoethyl)thiosemicarbazone | HCID 54402859 | — |
반응 단계
A mixture of 6.00 g (0.0294 mole) of 4-(2-morpholinoethyl)thiosemicarbazide, 3.91 g (0.0323 mole) of 2-acetylpyridine, 20 mL of 95% ethanol, and 0.4 mL of glacial acetic acid was heated under reflux for 1.25 hours. The mixture then stood overnight at room temperature. Colourless crystals were collected and recrystallised from 40 mL of 95% ethanol; yield 7.81 g (86%) of pale yellow crystals of 2-acetylpryridine 4-(2-morpholinoethyl)thiosemicarbazone, mp 167.5°-169° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04758572 |
| 출처 데이터셋 | uspto-grants-1988_07 |
| ORD ID | ord-1146570031294c70b5319c308ba10868 |
| 출처 메모 | uspto-grants-1988_07 |