m-Chloroperbenzoic acid → HCID 178493618, compound

Participants

Reaction Conditions

Reaction Steps

A solution of 911 mg. (4.22 mmoles) of m-chloroperoxybenzoic acid in 50 ml. of chloroform was added in a dropwise fashion to a solution of 1.15 gm. (4.23 mmoles) 2-(2-methoxy-4-methylmercaptophenyl)imidazo[4,5-c]pyridine in 150 ml. of chloroform at 0° C. The reaction was stirred overnight at 0° C., washed with dilute aqueous sodium bicarbonate, and the solvent removed in vacuo. The residue was flash chromatographed over silica gel using dichloromethane/methanol (9:1) affording 620 mg. (51% yield) of the title product, m.p. about 143°-146° C. (decomposition).

Provenance & Evidence