反应详情

A mixture of 3.0 g of 3-phenyl-1,2,4-thiadiazole-5-sulfonamide and 10 ml of triethyl orthoacetate was warmed at reflux for 4 hours. The mixture was cooled to room temperature and diluted with hexane (30 ml) and the precipitated solid was collected, washed with hexane and dried to give 3.25 g of solid, m.p. 120°-122°.

1. temperaturewas warmed
2. temperatureat reflux for 4 hours
3. customthe precipitated solid was collected
4. washwashed with hexane
5. customdried