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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 84548Generated: October 29, 2026

Morpholine → HCID 57900218, compound

https://huagongshe.com/reaction/84548

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMorpholineHCID 8083—
ReactantN-(2-chlorophenyl)-N-methyl-8-((methylamino)methyl)-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamideHCID 56833639—
Reactant8-(Bromomethyl)-N-(2-chlorophenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamideHCID 56834152—
ProductHCID 57900218HCID 57900218—

Reaction Steps

Following the procedure in Example 153 for the synthesis of 243, 8-(bromomethyl)-N-(2-chlorophenyl)-N-methyl-4,5-dihydrobenzo[b]thieno[2,3-d]oxepine-2-carboxamide was reacted with morpholine to give 261. MS: (ESI+) 469.0

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08846762B2
Source datasetuspto-grants-2014_09
ORD IDord-5542f0fd9a354792926842e5e127e49f
Source noteuspto-grants-2014_09