Sulfuric Acid → HCID 56994825, compound

Participants

Reaction Steps

For example, a solution of 4-n-butylglyoxylanilide (II), (12.2 g, 0.01 mole) is added to concentrated sulfuric acid (23 ml) at 50° C. while maintaining the reaction mixture by cooling below 65° C. The mixture is held at 65° C. for one hour an poured unto ice with stirring. A reddish-orange precipitate is formed and is washed with water. Recrystallization from ethanol yields pure 5-n-butyl-octahydro-2,3-dioxo-1H-indole (III) with mp 112°-113° C.

Provenance & Evidence