Benzaldehyde → HCID 178496300, compound

Participants

Reaction Steps

The reaction of hydroxylamine 55 (0.80 g, 2 mmol) with benzaldehyde (56)(0.21 g, 2 mmol) afforded, after workup, a yellow oil. The crude product was purified by flash chromatography with 1:1 ethyl acetate/hexane as the eluant to obtain 0.85 g (1.72 mmol, 86%) of 67 as a light yellow gum; IR (CH2Cl2) 3440, 2975, 1692, 1620, 1552, 1470, 1298, 1212, 1100 cm-1 ; 1H NMR (CDCl3, 60 MHz) δ 1.16 (t, J=6 Hz, 6H), 2.26 (s, 6H), 3.30 (s, 3H), 3.50 (t, J=5 Hz, 2H), 4.16 (t, J=5 Hz, 2H), 4.70-5.06 (m, 2H), 6.86 (bs, 1H), 7.30-8.46 (m, 10H). Anal. Calcd for C28H32N2O6 : C, 68.29; H, 6.50. Found: C, 68.16; H, 6.31.

Provenance & Evidence