HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylhydrazine hydrochloride → HCID 86741572, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylhydrazine hydrochloride | HCID 60962 | — |
| Reactant | Sodium Acetate | HCID 517045 | — |
| Reactant | 4-(2-Fluorobenzoyl)-1-methylpiperidine | HCID 13180317 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | HCID 86741572 | HCID 86741572 | 83% |
Reaction Steps
A mixture of 14.6 g of 4-(2-fluorobenzoyl)-1-methylpiperidine, 12.0 g of phenylhydrazine hydrochloride and 16.0 g of sodium acetate in 280 ml of n-butanol was heated under reflux for 3.5 hrs. The reaction mixture was cooled, filtered and concentrated. The residue was washed with ether to yield 17 g (83% ) of 4-(2-fluorobenzoyl)-1-methylpiperidine phenylhydrazone, mp 131°-134° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04758668 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-12838f99827d42edb9f5096d7c6b3288 |
| Source note | uspto-grants-1988_07 |