Acetone → HCID 20130085, compound

Participants

Reaction Steps

The above chloromethylcarbamate of thiabendazole (1 g) was dissolved in acetone (50 ml) and stirred at room temperature with sodium iodide (1 g) for 72 hours. The acetone was evaporated off. The residue taken in chloroform was washed with water, aqueous sodium bisulfite and water. The chloroform solution was evaporated to furnish 1.2 g of a light yellow solid which tended to decompose on attempting crystallize from EtOAc. NMR (CDCl3) δ6.03 (2H, s, OCH2I), 7.3-8.1 (5H, m, aromatic) and 8.96 (1H, d, J=3 Hz, aromatic).

Provenance & Evidence