Phosgene → 2,2-Dimethyl-1,3-dioxolan-4-ylmethyl chloroformate

HRID 845725Notes

Reaction equation

HRID 845725 reaction equation
[C:1](Cl)([Cl:3])=[O:2].[CH3:5][C:6]1([CH3:13])[O:10][CH:9]([CH2:11][OH:12])[CH2:8][O:7]1>C1C=CC=CC=1.C(Cl)Cl>[Cl:3][C:1]([O:12][CH2:11][CH:9]1[CH2:8][O:7][C:6]([CH3:13])([CH3:5])[O:10]1)=[O:2]

Participants

5

Reactant 2

HCID 6371PhosgeneHCID 7528Solketal

Product 1

HCID 156114432,2-Dimethyl-1,3-dioxolan-4-ylmethyl chloroformate

Reagents, catalysts & solvents 2

HCID 241BenzeneSolventHCID 6344DichloromethaneSolvent

Procedure

10 ml of a 10% w/v solution of phosgene in benzene were added to a solution of 1.0 g of 2,3-isopropylideneglycerol in 5 ml of methylene chloride, and the mixture was allowed to react overnight at room temperature. The mixture was then concentrated by evaporation under reduced pressure, giving 1.47 g of the title compound as a liquid.

Workup

  1. customto react overnight at room temperature
  2. concentrationThe mixture was then concentrated by evaporation under reduced pressure

Sources & evidence

ORD record
ord-d1a180b5d8e04457ad6e1d23b8c4e260
Source dataset
uspto-grants-1988_07
Patent number
US04760054

Reaction notes

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