HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Aspartame
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | Water | HCID 962 | — |
| Reactant | N-(N-Formyl-L-alpha-aspartyl)-3-phenyl-L-alanine | HCID 92472 | — |
| Product | Aspartame | HCID 134601 | — |
Reaction Steps
deformylating formyl-α-L-aspartyl-L-phenylalanine in the presence of hydrogen chloride, methanol and water. Then, adding methanol and hydrogen chloride directly to the resulting solution to obtain the chloride salt of α-L-aspartyl-L-phenylalanine methyl ester.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04760164 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-b49355ec17c74449a2520f629623693e |
| Source note | uspto-grants-1988_07 |