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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 845869Generated: October 30, 2026

L-Phenylalanine → N-(N-Formyl-L-alpha-aspartyl)-3-phenyl-L-alanine

https://huagongshe.com/reaction/845869

Reaction equation

Participants

RoleNameHCIDCharge
ReactantL-PhenylalanineHCID 6140—
ReactantN-[(3S)-Tetrahydro-2,5-dioxo-3-furanyl]formamideHCID 11298025—
SolventWaterHCID 962—
ProductN-(N-Formyl-L-alpha-aspartyl)-3-phenyl-L-alanineHCID 92472—

Reaction Steps

reacting the formyl-L-aspartic anhydride of formula (II) with the L-phenylalanine in the presence of water at a pH 9-13 and at a temperature of from about -5° C. to 5° C., to produce a formyl-L-aspartyl-L-phenylalanine;

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04760164
Source datasetuspto-grants-1988_07
ORD IDord-b4efef8d90664cd6a4c2096cd86e5387
Source noteuspto-grants-1988_07