HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acrylamide → Ethyl (acryloylamino)(hydroxy)acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acrylamide | HCID 6579 | — |
| Reactant | Ethyl 2-ethoxy-2-hydroxyacetate | HCID 95630 | — |
| Reactant | Ethyl 2-ethoxy-2-[(1-oxo-2-propen-1-yl)amino]acetate | HCID 57306758 | — |
| Product | Ethyl (acryloylamino)(hydroxy)acetate | HCID 18997977 | — |
Reaction Steps
Ethyl glyoxylate hemiacetal obtained from Example A in the amount of 29.5 parts (0.2 mole) is employed along with 14.3 parts (0.2 mole) of acrylamide following the procedure of Example I. The reaction is run at 70°-85° C. for 2.5 hours. Analysis of the product by 13C NMR shows a 90% conversion with a 90% selectivity to ethyl acrylamidoglycolate ethyl ether are also found.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04760168 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-d8ac2cd86df04edc8cb3f0ae0a704247 |
| Source note | uspto-grants-1988_07 |