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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 845918Generated: October 26, 2026

Sodium → isopropyl 2-chloro-5-[3,6-dihydro-4-methyl-6-oxo-2-thioxo-1(2H)-pyrimidinyl]-benzoate

https://huagongshe.com/reaction/845918

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodiumHCID 5360545—
ReactantIsopropyl 2-chloro-5-{3-[2-(ethoxycarbonyl)-1-methylvinyl]thioureido}-benzoateHCID 54245261—
SolventIsopropanol dimethylformamideHCID 20197112—
Productisopropyl 2-chloro-5-[3,6-dihydro-4-methyl-6-oxo-2-thioxo-1(2H)-pyrimidinyl]-benzoateHCID 20130634—

Reaction Steps

using isopropyl 2-chloro-5-{3-[2-(ethoxycarbonyl)-1-methylvinyl]thioureido}-benzoate with sodium isopropylate in an isopropanol/dimethylformamide mixture there is obtained isopropyl 2-chloro-5-[3,6-dihydro-4-methyl-6-oxo-2-thioxo-1(2H)-pyrimidinyl]-benzoate,

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04760163
Source datasetuspto-grants-1988_07
ORD IDord-0e6a8a14789a48e2837ed9956cffea45
Source noteuspto-grants-1988_07