Ethyl 3-oxohexanoate → HCID 54418963, compound
Reaction equation
[Cl:1][C:2]1[CH:13]=[C:12]([F:14])[C:11]([NH:15][C:16]([NH2:18])=[O:17])=[CH:10][C:3]=1[C:4]([O:6][CH:7]([CH3:9])[CH3:8])=[O:5].O=[C:20]([CH2:27][CH2:28][CH3:29])[CH2:21][C:22]([O:24][CH2:25][CH3:26])=[O:23]>>[Cl:1][C:2]1[CH:13]=[C:12]([F:14])[C:11]([NH:15][C:16]([NH:18][C:20]([CH2:27][CH2:28][CH3:29])=[CH:21][C:22]([O:24][CH2:25][CH3:26])=[O:23])=[O:17])=[CH:10][C:3]=1[C:4]([O:6][CH:7]([CH3:9])[CH3:8])=[O:5]Participants
3
Procedure
using isopropyl 2-chloro-4-fluoro-5-ureidobenzoate and ethyl 3-oxo-caproate there is obtained isopropyl 2-chloro-4-fluoro-5-{3-[2-(ethoxycarbonyl)-1-propylvinyl]ureido}-benzoate,
Sources & evidence
- ORD record
- ord-66e14f9b52444a638bd11e92d3e450ad
- Source dataset
- uspto-grants-1988_07
- Patent number
- US04760163
Reaction notes
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