HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Butenoic acid, 3-amino-, ethyl ester, (2Z)- → Ethyl 2-chloro-5-{3-[2-(ethoxycarbonyl)-1-methylvinyl]ureido}-benzoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Butenoic acid, 3-amino-, ethyl ester, (2Z)- | HCID 643756 | — |
| Reactant | Ethyl 2-chloro-5-isocyanatobenzoate | HCID 14255153 | — |
| Product | Ethyl 2-chloro-5-{3-[2-(ethoxycarbonyl)-1-methylvinyl]ureido}-benzoate | HCID 53941954 | — |
Reaction Steps
using ethyl 2-chloro-5-isocyanatobenzoate and ethyl 3-aminocrotonate there is obtained ethyl 2-chloro-5-{3-[2-(ethoxycarbonyl)-1-methylvinyl]ureido}-benzoate, using isopropyl 2-chloro-4-fluoro-5-isocyanatobenzoate and ethyl 3-aminocrotonate there is obtained isopropyl 2-chloro-4-fluoro-5-{3-[2-(ethoxycarbonyl)-1-methylvinyl]ureido}benzoate, m.p. 147°-150° C.,
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04760163 |
| Source dataset | uspto-grants-1988_07 |
| ORD ID | ord-53b7aff5d2414ea8b5de9f15ab77ef4f |
| Source note | uspto-grants-1988_07 |